GLP-1 Medication Comparison: Ozempic vs Wegovy vs Mounjaro vs Zepbound
A side-by-side comparison of the major GLP-1 medications: molecule, dosing, cost, FDA indication, side effects, and average weight loss. Pick the right one for your situation.
Most weight-loss apps were built for willpower dieting.
GLP-1 medications are not willpower dieting. They kill appetite — and that is both the benefit and the danger. Under-eat protein on these drugs and you lose muscle, slow your metabolism, and rebound the moment you stop. Sharpy is built around one question:
When the medication stops, what will you have left?
What's inside Sharpy
Six features designed around how GLP-1s actually feel — appetite suppression, muscle risk, and the maintenance phase nobody plans for.
Protein-forward meals
Plans designed around appetite-suppressing side-effects: nausea, early fullness, food aversion. Real food, portioned for your dose and goal weight.
Muscle-preserving workouts
GLP-1 drugs cause fat AND muscle loss. Sharpy leans on resistance training proven to protect lean mass — so the loss stays off.
Daily Shape Score
A single number from 0–100 that grades how well you hit protein, hydration, movement, sleep, and strength training today.
Weight & body tracking
Log your weight, watch the trend, and beat your Shape Score — without the calorie-counting theatrics.
GLP-1 Learn Hub
Plain-English articles on side-effect management, protein targets, hydration, the maintenance phase, and life after the medication.
On-device privacy
Your weight, meals, and workouts never leave your iPhone. No accounts, no ads, no data brokers — ever.
The Shape Score
A single number from 0–100 that grades how well you hit the six factors that matter on a GLP-1 plan. No calorie counting. No food shame. Just a daily target you'll want to beat.
78Today's Shape
Six factors. One score.
- Protein hit — based on your weight and dose
- Hydration — water targets that account for GLP-1 dehydration risk
- Movement — daily steps and active minutes
- Strength training — sessions that protect lean mass
- Sleep — recovery for a healthy metabolism
- Consistency — yesterday's score isn't your destiny
Built different. On purpose.
Most weight-loss apps
- Calorie deficit math, designed for willpower
- Generic meal plans built for hungry users
- Cardio-heavy programs that burn muscle
- No plan for "what happens when I stop"
- Hungry users → high churn
Sharpy
- Protein floor first — built for appetite suppression
- Side-effect aware meals (nausea, early fullness, aversions)
- Resistance training to protect lean mass
- A real maintenance phase, with a transition plan
- One Shape Score you'll actually want to beat
From the Learn Hub
Plain-English guides for the GLP-1 generation — covering medication, diet, side-effect management, and the maintenance phase nobody plans for. 78+ articles.
GLP-1 and Pregnancy: Why You Need to Stop Before Trying to Conceive
GLP-1 medications are not approved for pregnancy or breastfeeding. Here is the timing protocol, fertility implications, and what to know if you become pregnant unexpectedly.
GLP-1 and Cardiovascular Health: The SELECT Trial and Beyond
GLP-1 medications reduce major cardiovascular events independently of weight loss. Here is what the SELECT trial showed and what it means for who should be on these drugs.
GLP-1 for Binge Eating Disorder: How These Drugs Help (and the Cautions)
Binge eating disorder is the most common eating disorder, and GLP-1 medications often dramatically reduce binge episodes. Here is what to know — and the eating disorder cautions.
12 Common Myths About GLP-1 Medications, Debunked
From "it just makes you sick" to "Ozempic causes cancer" — here are the most common GLP-1 myths and what the actual evidence says.
GLP-1 for Fatty Liver Disease (NAFLD/MASH): Why It Works
Non-alcoholic fatty liver disease (now called MASH) responds dramatically to GLP-1 medications. Here is the mechanism, the data, and what to expect.